Evidence and Consensus-Based German Guidelines for the Management of Analgesia, Sedation and Delirium in Intensive Care – Short Version


Jörg Martin, Anja Heymann, Katrin Bäsell, Ralf Baron, Rolf Biniek, Hartmut Bürkle, Peter Dall, Christine Dictus, Verena Eggers, Ingolf Eichler Lothar Engelmann, Lars Garten, Wolfgang Hartl, Ulrike Haase, Ralf Huth, Paul Kessler, Stefan Kleinschmidt, Wolfgang Koppert, Franz-Josef Kretz, Heinz Laubenthal, Guenter Marggraf, Andreas Meiser, Edmund Neugebauer, Ulrike Neuhaus, Christian Putensen, Michael Quintel, Alexander Reske, Bernard Roth, Jens Scholz, Stefan Schröder, Dierk Schreiter, Jürgen Schüttler, Gerhard Schwarzmann, Claudia Spies, Robert Stingele, Peter Tonner, Philip Tränkle, Rolf Detlef Treede, Tomislav Trupkovic, Michael Tryba, Frank Wappler, Christian Waydhas



GMS German Medical Science 2010, Vol. 8 



Targeted monitoring of analgesia, sedation and delirium, as well as their appropriate management in critically ill patients is a standard of care in intensive care medicine. With the undisputed advantages of goal-oriented therapy established, there was a need to develop our own guidelines on analgesia and sedation in intensive care in Germany and these were published as 2nd Generation Guidelines in 2005. Between 2006–2009, the existing guidelines from the DGAI (Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin) and DIVI(Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin) were developed into Generation Guidelines for the securing and optimization of quality of analgesia, sedation and delirium management in the intensive care unit (ICU). In collaboration with another 10 professional societies, the literature has been reviewed using the criteria of the Oxford Center of Evidence Based Medicine. Using data from 671 reference works, texts, diagrams and recommendations were drawn up. In the recommendations, Grade “A” (very strong recommendation), Grade “B” (strong recommendation) and Grade “0” (open recommendation) were agreed. As a result of this process we now have an interdisciplinary and consensus-based set of 3rd Generation Guidelines that take into account all critically illness patient populations. The use of protocols for analgesia, sedation and treatment of delirium are repeatedly demonstrated. These guidelines offer treatment recommendations for the ICU team. The implementation of scores and protocols into routine ICU practice is necessary for their success.





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A new frontier in critical care: saving the injuried brain.

Link veloci

Gestire il dolore

ico-flowchartdoloreFlowchart dolore

Gestire la sedazione

ico-flowchart-sedaz-agitFlowchart sedaz/agitaz

Gestire il delirium

ico-flowchart-deliriumFlowchart Delirium
ico-manuale-cam-icuManuale CAM-ICU
ico-schedalavoro-cam-icuScheda di lavoro CAM-ICU


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